The Permatan solution leverages the skin's natural tanning potential through use of biomimetics.
The way the body makes the melanin which provides a natural tan is by way of converting the amino acid Tyrosine via the enzyme Tyrosinase. The Permatan exclusive complex is designed to increase the bioavailability of both this enzyme and substrate amino acid Tyrosine, all of which are required for melanogenesis (melanin production). By increasing the bioavailability of these compounds in the skin, the amount of melanin produced is increased and the body produces a natural tan quicker.
Normally, this process is regulated by the hormone alpha-MSH which is responsible for skin darkening, however, the Permatan formula enables an increase of melanogenesis even when alpha-MSH levels are low (i.e in individuals that are normally fair and cannot normally obtain a natural tan). It is important to note, however, that the Permatan formula does not contain alpha-MSH itself and also does not interfere with the body's natural levels of other hormones.
The solution is able to be absorbed by the nasal membrane and sublingual glands as our solution has molecules small enough to pass through these membranes. These membranes in particular are ideal for absorption as they are only a few cells thick.
Permatan was designed to require very minimal sun exposure to be effective as it results in increased levels of eumelanin. When a person's eumelanin levels are increased, only a very small amount of sun is required to leverage the tanning potential of the eumelanin and provide a noticeable colour change.
It is this technology that differentiates Permatan from other traditional tanning methods, allowing for game-changing results that speak for themselves.